ANTHONY P TRAN, PAULO N MARTİNS, ZACHARY G PAPAZİAN, VİJAY K VANGURİ, BABAK MOVAHEDİ, PANG YEN FAN, KENNETH A BODZİAK, JENNİFER K YATES, MİTCHELL H SOKOLOFF, ADEL BOZORGZADEH
Experimental and Clinical Transplantation - 2021;19(7):732-735
With the rising incidence of end stage renal disease in the United States, patients needing renal transplants are waiting longer for increasingly scarce grafts. Formerly, the general practice was to avoid organs with tumors for transplant because of the risk of malignancy transmission to the recipient. However, with comprehensive donor selection and a small sized primary tumor, the positive outcomes of transplant outweigh the risks of transmission after a partial nephrectomy. In our case, a 31 year old woman, the daughter of the recipient, underwent a laparoscopic nephrectomy with an existing 8 mm tumor later confirmed as renal cell carcinoma. An ex vivo tumor enucleation was performed before the allograft was transplanted into the 69 year old patient with endstage renal disease. At last follow up, graft function has remained excellent with no evidence of local recurrence or metastasis in both the donor and recipient. Here, we describe our case and perform a literature review on the incidence and management of renal allografts with incidentally detected renal cell carcinoma during transplant.
