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URINE IODINE DEFICIENCY IN PREGNANT WOMEN LIVING IN SIVAS

HALEF OKAN DOĞAN, ÖZGÜR KARAKAYA, KÜBRA DOĞAN, SAVAŞ KARAKUŞ, ŞEYMA NUR YILDIZ

Annals of Clinical and Analytical Medicine - 2018;9(4):269-272

Department of Biochemistry, Faculty of Medicine, Cumhuriyet University

 

Aim: The study aimed to assess the iodine status and maternal thyroid function in the pregnant women in Sivas that is a city in central Turkey. Material and Method: One hundred-ninety-three pregnant women in their second trimester who attended the hospital for routine antenatal care were included this study. Morning spot urine samples were collected in deiodized test tubes from the study population. Urine iodine levels were determined by colorimetric modified Sandell-Kolthoff reaction. Serum free triiodothyronine (fT3), free thyroxine (fT4) and thyrotropin (TSH) levels were measured by electrochemiluminescence immunoassays. Results: Median urine iodine levels were lower in Şarkışla, Suşehri Gürün, Divriği and Kangal than Sivas Center. Median urine iodine deficiency levels of pregnant women living in Şarkışla, Suşehri Gürün, Divriği, and Kangal indicated mild iodine deficiency. Discussion: Iodine deficiency is a significant problem in Sivas. Therefore, there is need for a policy such as iodine prophylaxis for pregnant women living in Sivas to eliminate this problem.