Wan LI, Ping HU, Jie WANG, Xiao-Jing MA, Yi GAO
The Anatolian Journal of Cardiology - 2026;30(4):0-0
A 57-year-old man presented with progressive exertional dyspnea and paroxysmal nocturnal dyspnea over 2 weeks. On auscultation, a low-pitched diastolic rumbling murmur was audible at the apex. Transthoracic echocardiography revealed a large, mobile mass (7.5 x 4.5 cm) attached to the mid-atrial septum, prolapsing into the mitral orifice during diastole and generating a mean transvalvular gradient of 32 mm Hg. Strikingly, a second, well-circumscribed mass (2.7 x 2.0 cm) was identified in the right ventricular outflow tract, with no internal vascularity on Doppler imaging. Contrast-enhanced cardiac computed tomography confirmed dual intracardiac masses and visualized a patent foramen ovale (PFO) connecting the 2 chambers. Both tumors were surgically resected, and histopathology confirmed identical benign myxoma morphology in both specimens-stellate cells embedded in a myxoid stroma. The patient recovered uneventfully and remained recurrence-free at 2-year follow-up.
