ABDURRAHMAN ALP TOKALİOGLU, NAZLİ TUNCA SANLİER, OKAN AYTEKİN, GUNSU KİMYON COMERT, FATİH KILIÇ, TANER TURAN
Annals of Clinical and Analytical Medicine - 2024;15(10):717-720
Aim: Our study aimed to analyze the single “other high-risk HPV type” and its’ relationship to the final pathology results. Material and methods: The study was conducted retrospectively, and data was collected from a specialized outpatient clinic for gynecologic oncology colposcopy unit. We analyzed data from 3546 patients who tested high-risk HPV positive and underwent colposcopic examination from September 2019 to December 2022. The study included 333 patients, each with a single “other high-risk HPV type” positive. Results: A total of 333 patients with a median age of 43 years (range, 2266 years) were analysed. In study cohort 68 (20.4%) patients were HPV 31, 19 (5.7%) patients were HPV 33, 19 (5.7%) patients were HPV 35, 24 (7.2%) patients were HPV 39, 22 (6.6%) patients were HPV 45, 39 (11.7%) patients were HPV 51, 40 (12%) patients were HPV 52, 41 (12.3%) patients were HPV 56, 15 (4.5%) patients were HPV 58, 18 (5.4%) patients were HPV 59 and 28 (8.4%) patients were HPV 68. Final pathologic results were benign in 168 (50.5%) patients, LSIL in 139 (41.7%) patients, HSIL (CIN 2) in 16 (4.8%) patients, HSIL (CIN 3) in 8 (2.4%) patients, HSIL (undefined) in 1 (0.3%) patient, and cancer in 1 (0.3%) in patient. There was no statistically significant correlation observed between the type of HPV and the presence of a ≥CIN2 lesion. Patients who tested positive for the single HPV 33 type had a higher prevalence of ≥CIN2 lesions. Discussion: In summary, other high-risk HPV types can serve as a criterion for referring high-risk HPV positive patients to colposcopy. Patients with HPV 33 positive test results need to be managed more carefully.
