WHIPPLE OF WHIPPLE’S TRIAD

TOMÁS GONZÁLEZ VİDAL, ELİAS DELGADO, EDELMİRO MENÉNDEZ TORRE

Journal of Clinical Practice and Research - 2023;45(6):655-657

Department of Endocrinology and Nutrition, Hospital Universitario Central de Asturias/University of Oviedo, Spain

 

Allen Oldfather (A. O.) Whipple (1881–1963) is renowned for giving rise to two medical ep-onyms: Whipple’s Triad, for the diagnostic criteria in hypoglycemia, and Whipple’s proce-dure, for the cephalic duodenopancreatectomy. Notably, A. O. Whipple’s life coincided with that of the unrelated George Hoyt Whipple, who is credited with the third eponymous Whip-ple in medicine – Whipple’s disease, or intestinal lipodystrophy. Nearly a century after its first description, Whipple’s Triad continues to be a valuable tool, comprising a set of symptoms and laboratory data that raise the clinical suspicion of hypoglycemia resulting from endog-enous hyperinsulinism.